Home Tools
Log in
Cart

Search Result

Search Results for " allosteric agonist "

20

Compounds

Cat No. Product Name Synonyms Targets
T8868 4BP-TQS AChR
4BP-TQS is an allosteric agonist of α7 nAChRs.
T10573 BMT-145027 GluR
BMT-145027 is a positive allosteric modulator of mGluR5 without inherent agonist activity (EC50 = 47 nM).
T17300 (-)-(S)-B-973B AChR
(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.
T3565 VU0155041 UV0155041,VU-0155041 GluR
VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).
T11458 GPR40/FFAR1 modulator 1 GPR
GPR40/FFAR1 modulator 1 is a Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1) agonist and allosteric modulator.
T1760 TBPB AChR
TBPB is an allosteric M1 mAChR agonist.
T3961 CYM-5541 CYM 5541,ML249,CID-17253208 S1P Receptor , LPL Receptor
CYM-5541 (ML249) is a selective and allosteric S1P3 receptor agonist.
T6575 LY2119620 AChR
LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.
T8403 Cinacalcet AMG 073 CaSR
Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease .
T12192 NCGC00229600 Others , TSH Receptor
NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies.
T2635 Org 27569 Cannabinoid Receptor
Org 27569, an allosteric modulator of cannabinoid CB1 receptor, can induce a CB1 receptor state that is characterized by decreased inverse agonist affinity and enhanced agonist affinity.
T8642 4-CMTB GPR
4-CMTB is a selective agonist of FFA2 and GPR43.It also is a positive allosteric modulator (pEC50=6.38).
T22703 CYM-5520 CYM 5520 S1P Receptor , LPL Receptor
CYM-5520 is a noncompetitive allosteric agonist of S1P2
T10814 Cinacalcet metabolite M4 Rarechem AL BW 1078 Calcium Channel
Cinacalcet metabolite M4 (Rarechem AL BW 1078) is a metabolite of Cinacalcet. Cinacalcet is an allosteric agonist of Ca receptor.
T8224 VU0119498 AChR
VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.
T7165 Basmisanil RG1662,RO5186582 GABA Receptor
Basmisanil (RG1662) is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the treatment of cognitive impairments associated with Down syndro...
T22301 L-838417 D9 CTP354,CTP354 (C-21191),C-21191 GABA Receptor
L-838417 D9 (C-21191) is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].
T12165 NAChR agonist 1 DUN71755 AChR
nAChR agonist 1 (DUN71755) is a brain-permeable and orally efficacious positive allosteric α7 nicotinic acetylcholine receptor (α7 nAChR)modulator.
T15363 FzM1.8 Wnt/beta-catenin
FzM1.8 is an allosteric FZD4 agonist with a pEC50 of 6.4. FzM1.8 binds to FZD4, promotes TCF/LEF transcriptional activity in the absence of any WNT ligand, and activates the WNT/β-catenin pathway.
T21935L AMN082 free base AMN082 GluR
AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist.
1 2 3 4
TargetMol